Dear Mr. Hoffman,
I write with much interest in your open Instrumentation Engineer position, I found advertised on your website last week. I am here to tell you that I am the best person for this position, and have enclosed my resume for proof.
Briefly, I have a Masters in Engineering, and over 11 years hands on experience as an Instrumentation Engineer. I have much experience in developing systems and instrument applications that optimize systems for internal and external use. I can design and implement new products for this purpose, and also optimize existing programs, systems, and applications to this end. I have a highly analytical mind, am super accurate in all my calculations, and have great interpersonal skills.
If you would like to meet with me, to learn more about my background, I suggest you contact me at (555)-555-5555 to arrange for an interview. Thanks so much for your time and consideration.